Opioid receptors are a group of receptors in the nervous system, and kratom’s principal alkaloids interact with one of them, the mu-opioid receptor. This interaction is the basis of much of the scientific interest in how kratom works.
Research describes kratom’s mitragynine and 7-hydroxymitragynine as acting at the mu-opioid receptor differently from classic opioids, a distinction that is an active area of study. This is a description of pharmacology, not a statement about treating any condition. See Kratom Alkaloids Explained and 7-Hydroxymitragynine.
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Disclaimer: This glossary entry is for educational purposes only and is not intended as medical, legal,
or professional advice. Kratom is not approved by the FDA to diagnose, treat, cure, or prevent any disease.